"Finally, from so little sleeping and so much reading, his brain dried up and he went completely out of his mind.” (Miguel de Cervantes Saavedra, Don Quixote)
The human nature always prevails
LEONATO:
For there was never yet philosopher
That could endure the toothache patiently,
However they have writ the style of gods
And made a push at chance and sufferance.
William Shakespeare - Much ado about nothing (5.1)